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A novel stem cell solution for preventing ischemia-induced amputations

Across the United States, about 2 million people are living with an amputation and another 185,000 amputations occur every year, according to the Amputee Coalition, a Washington DC-based support group.

19 Dec 2023

Study reveals hidden inactive form of p38a protein

p38a protein, a key enzyme in the regulation of various cellular functions, plays a crucial role in some diseases, including cancer, chronic inflammation, and neurodegenerative conditions.

19 Dec 2023

Groundbreaking genome-editing technique holds promise for treating Charcot–Marie–Tooth disease

Scientific advances in the last century have changed our world significantly. For example, the world of genetics has opened doors to a myriad of possibilities: augmented human capabilities, cures for diseases, and even changes to the course of evolution.

19 Dec 2023

Patient-specific muscle models pave way for personalized neuromuscular therapies

Scientists have so far identified around 800 different neuromuscular diseases. These conditions are caused by problems in the way muscle cells, motor neurons and peripheral cells interact.

19 Dec 2023

Kyoto scientists map double whammy gene clusters for anxiety disorders

Anxiety disorders (ADs) affect more than 280 million people worldwide, making them one of the most common mental health conditions. ADs have a genetic basis as seen from inheritance in families, and people with one subtype of AD tend to have another subtype, suggesting a shared genetic basis.

19 Dec 2023

From Neanderthals to now: Tracing the evolution of human sleep cycles

Researchers examined the differences in circadian biology between the ancestors of modern humans and the archaic hominins such as Denisovans and Neanderthals and the contribution of archaic introgression in human chronotypes by using genomes to trace chronotype evolution from archaic hominins to modern-day humans.

19 Dec 2023

Bridging ideas to IND: Nona Biosciences' year of impact in biotechnology

Amidst a backdrop of industry-wide hurdles like inflation, talent scarcities, and stringent regulatory landscapes, Nona Biosciences is showing great promise as an emerging global leader in biotechnology.

From Nona BioSciences 19 Dec 2023

Key Charpentier/Doudna CRISPR patent upheld by Japanese Patent Office

Patent JP6692856 upheld for second time in response to invalidation challenge.

19 Dec 2023

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Researchers investigated the anticancer effects of drugs targeting human tumor-associated macrophages (TAMs) in vivo. In humanized murine models, they tested the effectiveness of an antibody to human signal regulatory protein alpha (SIRPα) for cancer immunotherapy.

19 Dec 2023

“Forever chemicals” could contribute to cancer metastasis in living organisms

In a new study by researchers at the Yale School of Public Health, two "forever chemicals" spurred cancer cells in the lab to migrate to new positions, an indication that the chemicals could contribute to cancer metastasis in living organisms.

18 Dec 2023

Leaky gut linked to depressive disorders: New insights into microbiota-induced epigenetic changes

A study in the journal Genes highlights how a leaky gut can lead to depressive disorders through changes in gut microbiota-derived metabolites, emphasizing the role of diet, environmental factors, and probiotics in managing these conditions.

18 Dec 2023

Study reveals altered time perception in early Alzheimer's stages, offering potential early diagnostic marker

Study investigates time perception in Alzheimer's disease and its preclinical stage, subjective cognitive decline (SCD), revealing specific alterations in temporal processing that could be early markers of cognitive decline.

18 Dec 2023

Decoding the genome of world's biggest bacteria

Not all bacteria are created equal. Most are single-celled and tiny, a few ten-thousandths of a centimeter long. But bacteria of the Epulopiscium family are large enough to be seen with the naked eye and 1 million times the volume of their better-known cousins, E. coli.

18 Dec 2023

How exercise battles muscle fat: New gene holds the answer

Myosteatosis, or aging-related fat accumulation in skeletal muscles, is a leading cause of declines in muscle strength and quality of life in elderly adults.

18 Dec 2023

Scientists identify genetic and epigenetic culprits behind bilateral Wilms tumor

Children with bilateral Wilms tumor have a tumor in each of their kidneys -; a condition that strongly suggests an underlying genetic or epigenetic predisposition driving the disease.

18 Dec 2023

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Research pioneer Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named 2023 breakthrough of the year by the Science Magazine.

18 Dec 2023

Scientists crack the code for targeting cancer's 'death star' protein

Researchers at the Centre for Genomic Regulation in Barcelona, Spain, and the Wellcome Sanger Institute near Cambridge, UK, have comprehensively identified the allosteric control sites found in the protein KRAS.

18 Dec 2023

Oxidized amino acids signal damaged photosynthesis proteins for repair

Photosynthesis refers to the fundamental biological process of the conversion of light energy into chemical energy by chlorophyll (a green pigment) containing plants.

18 Dec 2023

Study unlocks muscle-boosting algae magic

With more of us looking for alternatives to eating animals, new research has found a surprising environmentally friendly source of protein – algae.

18 Dec 2023

Single-cell RNA sequencing generates comprehensive atlas of zebrafish development

Researchers at the National Institutes of Health have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a period in which embryos mature from a single cell into distinct cell types.

18 Dec 2023

Life Science News

A novel stem cell solution for preventing ischemia-induced amputations

Study reveals hidden inactive form of p38a protein

Groundbreaking genome-editing technique holds promise for treating Charcot–Marie–Tooth disease

Patient-specific muscle models pave way for personalized neuromuscular therapies

Kyoto scientists map double whammy gene clusters for anxiety disorders

From Neanderthals to now: Tracing the evolution of human sleep cycles

Bridging ideas to IND: Nona Biosciences' year of impact in biotechnology

Key Charpentier/Doudna CRISPR patent upheld by Japanese Patent Office

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

“Forever chemicals” could contribute to cancer metastasis in living organisms

Leaky gut linked to depressive disorders: New insights into microbiota-induced epigenetic changes

Study reveals altered time perception in early Alzheimer's stages, offering potential early diagnostic marker

Decoding the genome of world's biggest bacteria

How exercise battles muscle fat: New gene holds the answer

Scientists identify genetic and epigenetic culprits behind bilateral Wilms tumor

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Scientists crack the code for targeting cancer's 'death star' protein

Oxidized amino acids signal damaged photosynthesis proteins for repair

Study unlocks muscle-boosting algae magic

Single-cell RNA sequencing generates comprehensive atlas of zebrafish development

How medical manufacturing trends are evolving: From performance testing to 3D vision

Utilizing firefly liquid handling for laboratory developed tests

Immunopeptidomics offer new hope in cancer research

Latest Life Science News