Unlock endless possibilities
With a broad selection of nucleic acid derivatives and customized oligo building blocks from LGC Biosearch Technologies, create unique research-grade oligos for any purpose, from unlabeled PCR primers to highly- modified oligos.
Benefits of working with LGC
- ISO 9001:2015-certified quality management system
- 1000+ oligo modifications
- Proprietary oligo synthesis instrumentation
- Demonstrated ability to deliver high-quality complex oligos
How to configure and order custom oligos
Ordering online: Use the order now tab to configure and order your oligo(s) using our online tool. Select from one of our three distinct synthesis scales (50 nmol, 200 nmol, or 1 μmol).
Excel order form: If you are ordering many oligos or require orders of >1 μmol synthesis scale, please use this Build Your Oligo Excel order form with online upload and email submission options.
Choose from a diverse menu of options
With over a 1,000 modifiactions available, design your oligos precisely to your application. Frequently used functional groupings include:
- Quencher
- Spacer
- Thiol
- Amine
- Biotin
- Fluorophore
- Linkage
- Non-standard base
- Phosphate
The purification methods offered by Biosearch Technologies range from salt-free to Dual-HPLC. Achieve optimal results by exploring recommendations to find the best solution for your application.
Technical specifications
Source: Biosearch Technologies
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| Sequence length |
6-150 bases for DNA
6-80 bases for RNA
Inquire for longer oligos |
| Purification options |
Salt-free (desalted)
Reverse Phase Cartridge (RPC)
Reverse Phase HPLC (RP HPLC)
Anion Exchange HPLC (AX HPLC)
Dual HPLC (RP + AX HPLC) |
| Synthesis scales |
Standard synthesis scales
- 50 nmol (small)
- 200 nmol (medium)
- 1 μmol (large)
Delivered amounts are lower than the synthesis scale. The final yield (amount delivered) of the oligo is determined by the combination of the modifications requested, the complexity of the oligo design, and the stringency of purification selected.
Synthesis scales larger than 1 μmol
For synthesis scales larger than 1 μmol, please specify the exact yield delivered in the notes field in the Excel order form. |
| Modifications and bases |
Large selection of 5', 3', and internal modifications available
Bases include locked nucleic acid (LNA), 5-Nitroindole, Inosine, d-Uridine, 2'O-Me RNA and 2'O-MOE RNA |
| Quality control |
Mass spectrometry and UHPLC to verify identity and purity |
| Delivery format |
Dry or in solution (water, TrisHCl, T10E0.1, T10E1) |
Download SDS for unlabeled oligos
Download SDS for fluorescently-labeled oligos
Need further help?
Check out the frequently asked questions for oligos in tubes.